文件名称:Inference of Gene Relations from Microarray
文件大小:86KB
文件格式:PDF
更新时间:2012-09-28 13:37:18
Microarray
Abstract. We describe an application of Abductive Logic Programming (ALP) to the analysis of an important class of DNA microarray experiments. We develop an ALP theory that provides a simple and general model of how gene interactions can cause changes in observable expression levels of genes. Input to the procedure are the observed microarray results; output are hypotheses about possible gene interactions that explain the observed eects. We apply and evaluate our approach on microarray experiments on M.tuberculosis and S.cerevisiae.