INTRODUCTION TO BIOINFORMATICS
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=课程主页:http://ocw.metu.edu.tr/course/view.php?id=37,
Instructor: Tolga CAN
Added: 18 November 2009
Topic outline
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General
INTRODUCTION TO BIOINFORMATICS
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Topic 2
Introduction to biology, biological databases, and high-throughput data sources. Overview of bioinformatics problems.Pairwise sequence alignment algorithms: Dynamic programming
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Topic 3
Statistical significance of alignments - Part IStatistical significance of alignments - Part II
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Topic 4
Suffix Trees, Suffix Arrays -
Topic 5
Patterns, Profiles, and Multiple Alignments -
Topic 6
Hidden Markov ModelsWeek 5 Lecture Slides Continued
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Topic 7
Multiple Sequence Alignment AlgorithmsWeek 5 Lecture Slides Continued
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Topic 8
Midterm Review and Midterm Exam
- Phylogenetic trees
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Topic 9
Introduction to protein structuresStructure Prediction
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Topic 10
Protein Structure Prediction (continued) -
Topic 11
Protein Structure Prediction (continued) -
Topic 12
Structural Alignment of Proteins
(lecture notes continued) -
Topic 13
Microarray data normalization, analysisClustering techniques
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Topic 14
Introduction to Systems BiologyGene regulatory networks
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Topic 15
Construction and Analysis of protein networks:
Monte Carlo Sampling, Random Walks on Graphs- Final review